The answer is C. The program prints:
[48, 42, 21, 15, 8]
This answer was checked by running the program for real.
Why?
sort() puts the list in order, smallest first. reverse=True flips it, so the biggest comes first. It changes the list itself.
The code again
scores = [42, 8, 48, 15, 21]
scores.sort(reverse=True)
print(scores)
Try it: change one number in the program and predict the new output before you run it.